A combined approach for single-cell mRNA and intracellular protein expression analysis

A combined approach for single-cell mRNA and intracellular protein expression analysis

Here, the authors present SPARC, a scalable approach for simultaneously measuring mRNA expression levels and targeted intracellular protein levels in single cells. They use SPARC to measure dynamic expression changes in human cells during neuronal differentiation and show that mRNA levels are poor p...

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Bibliographic Details
Main Authors: Johan Reimegård, Marcel Tarbier, Marcus Danielsson, Jens Schuster, Sathishkumar Baskaran, Styliani Panagiotou, Niklas Dahl, Marc R. Friedländer, Caroline J. Gallant
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02142-w

Internet

https://doi.org/10.1038/s42003-021-02142-w

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