Requirements within the Ebola Viral Glycoprotein for Tetherin Antagonism

Tetherin is an interferon-induced, intrinsic cellular response factor that blocks release of numerous viruses, including Ebola virus, from infected cells. As with many viruses targeted by host factors, Ebola virus employs a tetherin antagonist, the viral glycoprotein (EboGP), to counteract restricti...

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Bibliographic Details
Main Authors: Nathan H. Vande Burgt, Rachel L. Kaletsky, Paul Bates
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:Viruses
Subjects:
sGP
Online Access:http://www.mdpi.com/1999-4915/7/10/2888