Promoter characterization and role of cAMP/PKA/CREB in the basal transcription of the mouse ORMDL3 gene.

Orosomucoid 1-like 3 (ORMDL3) gene was strongly linked with the development of asthma in genetic association studies, and its expression could be significantly induced by allergen in airway epithelial cells of mice. However, the expression mechanism of ORMDL3 was still unclear. Here we have identifi...

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Bibliographic Details
Main Authors: Li-Li Zhuang, Rui Jin, Liang-Hua Zhu, Hua-Guo Xu, Yue Li, Shan Gao, Jia-Yin Liu, Guo-Ping Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3618037?pdf=render