Decreased serum PON1 arylesterase activity in familial hypercholesterolemia patients with a mutated LDLR gene

Decreased serum PON1 arylesterase activity in familial hypercholesterolemia patients with a mutated LDLR gene

Abstract Paraoxonase 1 (PON1) is a serum enzyme associated with high density lipoprotein (HDL) regulation through its paraoxonase and arylesterase activity. PON1 inhibits the oxidation of HDL and low density lipoprotein (LDL), and is involved in the pathogenesis of a variety of diseases including at...

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Bibliographic Details
Main Authors: Muhammad Idrees, Abdul Rauf Siddiq, Muhammad Ajmal, Muhammad Akram, Rana Rehan Khalid, Alamdar Hussain, Raheel Qamar, Habib Bokhari
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2018-07-01
Series:Genetics and Molecular Biology
Subjects:
Paraoxonase-1
hypercholesteremia
arylesterase
LDLR mutation
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572018000400570&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572018000400570&lng=en&tlng=en

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