Aberrant Glycosylation Augments the Immuno-Stimulatory Activities of Soluble Calreticulin

Calreticulin (CRT), a luminal resident calcium-binding glycoprotein of the cell, is a tumor-associated antigen involved in tumorigenesis and also an autoantigen targeted by autoantibodies found in patients with various autoimmune diseases. We have previously shown that prokaryotically expressed reco...

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Bibliographic Details
Main Authors: Fang-Yuan Gong, Zheng Gong, Cui-Cui Duo, Jun Wang, Chao Hong, Xiao-Ming Gao
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/23/3/523