Mendelian randomization and experimental IUGR reveal the adverse effect of low birth weight on lung structure and function

Abstract Intrauterine growth restriction (IUGR) and low birth weigth (LBW) are risk factors for neonatal chronic lung disease. However, maternal and fetal genetic factors and the molecular mechanisms remain unclear. We investigated the relationship between LBW and lung function with Mendelian random...

Full description

Bibliographic Details
Main Authors: Celien Kuiper-Makris, Daniela Zanetti, Christina Vohlen, Luise Fahle, Marion Müller, Margarete Odenthal, Ursula Felderhoff-Müser, Jörg Dötsch, Miguel A. Alejandre Alcazar
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79245-7