Evaluating the SERCA2 and VEGF mRNAs as Potential Molecular Biomarkers of the Onset and Progression in Huntington's Disease.

Evaluating the SERCA2 and VEGF mRNAs as Potential Molecular Biomarkers of the Onset and Progression in Huntington's Disease.

Abnormalities of intracellular Ca2+ homeostasis and signalling as well as the down-regulation of neurotrophic factors in several areas of the central nervous system and in peripheral tissues are hallmarks of Huntington's disease (HD). As there is no therapy for this hereditary, neurodegenerativ...

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Bibliographic Details
Main Authors: Federica Cesca, Elisa Bregant, Borut Peterlin, Maja Zadel, Giorgia Dubsky de Wittenau, Gabriele Siciliano, Roberto Ceravolo, Lucia Petrozzi, Giada Pauletto, Lorenzo Verriello, Paolo Bergonzi, Giuseppe Damante, Giovanni Barillari, Bruno Lucci, Francesco Curcio, Incoronata Renata Lonigro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4411078?pdf=render

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http://europepmc.org/articles/PMC4411078?pdf=render

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