DNA Binding, Photonuclease Activity and Human Serum Albumin Interaction of a Water-Soluble Freebase Carboxyl Corrole

The DNA binding property of 5,10,15-Tris(4-carboxyphenyl) corrole (TCPC) was studied by UV-Visible, fluorescence and circular dichroism (CD) spectroscopic methods. TCPC can bind to ct-DNA via an outside binding mode with the binding constant of Kb = 1.05 × 105 M−1. TCPC also displayed good photonucl...

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Bibliographic Details
Main Authors: Ning Na, Da-Qiang Zhao, Heng Li, Nan Jiang, Jin-Yan Wen, Hai-Yang Liu
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Molecules
Subjects:
DNA
Online Access:http://www.mdpi.com/1420-3049/21/1/54