HDAC6 deacetylase activity is critical for lipopolysaccharide-induced activation of macrophages.

Activated macrophages play an important role in both innate and adaptive immune responses, and aberrant activation of macrophages often leads to inflammatory and immune disorders. However, the molecular mechanisms of how macrophages are activated are not fully understood. In this study, we identify...

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Bibliographic Details
Main Authors: Bing Yan, Songbo Xie, Zhu Liu, Jie Ran, Yuanyuan Li, Jian Wang, Yang Yang, Jun Zhou, Dengwen Li, Min Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4199742?pdf=render