PGRMC1 Inhibits Progesterone-Evoked Proliferation and Ca<sup>2+</sup> Entry Via STIM2 in MDA-MB-231 Cells

PGRMC1 Inhibits Progesterone-Evoked Proliferation and Ca<sup>2+</sup> Entry Via STIM2 in MDA-MB-231 Cells

Progesterone receptor membrane component 1 (PGRMC1) has been shown to regulate some cancer hallmarks. Progesterone (P<sub>4</sub>) evokes intracellular calcium (Ca<sup>2+</sup>) changes in the triple-negative breast cancer cell lines (MDA-MB-231, MDA-MB-468, and BT-20) and in...

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Bibliographic Details
Main Authors: Carlos Cantonero, Ginés M. Salido, Juan A. Rosado, Pedro C. Redondo
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
MDA-MB-231 cells
STIM2
PGRMC1
Ca<sup>2+</sup>-homeostasis
progesterone
Online Access:https://www.mdpi.com/1422-0067/21/20/7641

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https://www.mdpi.com/1422-0067/21/20/7641

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