Monitoring DNA Damage and Repair in Peripheral Blood Mononuclear Cells of Lung Cancer Radiotherapy Patients

Monitoring DNA Damage and Repair in Peripheral Blood Mononuclear Cells of Lung Cancer Radiotherapy Patients

Thoracic radiotherapy (RT) is required for the curative management of inoperable lung cancer, however, treatment delivery is limited by normal tissue toxicity. Prior studies suggest that using radiation-induced DNA damage response (DDR) in peripheral blood mononuclear cells (PBMC) has potential to p...

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Bibliographic Details
Main Authors: Pavel N. Lobachevsky, Nicholas W. Bucknell, Joel Mason, Diane Russo, Xiaoyu Yin, Lisa Selbie, David L. Ball, Tomas Kron, Michael Hofman, Shankar Siva, Olga A. Martin
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
non-small cell lung cancer
radiation therapy
DNA damage repair
Online Access:https://www.mdpi.com/2072-6694/12/9/2517

Internet

https://www.mdpi.com/2072-6694/12/9/2517

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