Targeted metabolomic analyses of cellular models of pelizaeus-merzbacher disease reveal plasmalogen and myo-inositol solute carrier dysfunction

Targeted metabolomic analyses of cellular models of pelizaeus-merzbacher disease reveal plasmalogen and myo-inositol solute carrier dysfunction

<p>Abstract</p> <p>Background</p> <p>Leukodystrophies are devastating diseases characterized by dys- and hypo-myelination. While there are a number of histological and imaging studies of these disorders, there are limited biochemical data available. We undertook targete...

Full description

Bibliographic Details
Main Authors: Pelzer Lindsay, Smith Tara, Wood Paul L, Goodenowe Dayan B
Format: Article
Language:English
Published: BMC 2011-06-01
Series:Lipids in Health and Disease
Subjects:
leukodystrophy
Pelizaeus-Merzbacher disease
fibroblasts
lymphocytes
158JP oligodendrocytes
plasmalogens
myo-inositol transporter
peroxisomal disorders
Online Access:http://www.lipidworld.com/content/10/1/102

Internet

http://www.lipidworld.com/content/10/1/102

Similar Items