Targeting claudin‐4 enhances chemosensitivity of pancreatic ductal carcinomas

Targeting claudin‐4 enhances chemosensitivity of pancreatic ductal carcinomas

Abstract Claudin (CLDN) family comprises of protein that form a tight junction, and is involved in regulating polarity and differentiation of cells. Here, we aimed to investigate the effects of inhibiting CLDN4 in pancreatic ductal carcinomas (PDC). We first examined 91 cases of human PDC by immunoh...

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Bibliographic Details
Main Authors: Takamitsu Sasaki, Rina Fujiwara‐Tani, Shingo Kishi, Shiori Mori, Yi Luo, Hitoshi Ohmori, Isao Kawahara, Kei Goto, Yukiko Nishiguchi, Takuya Mori, Masayuki Sho, Masuo Kondo, Hiroki Kuniyasu
Format: Article
Language:English
Published: Wiley 2019-11-01
Series:Cancer Medicine
Subjects:
claudin
tight junction
Online Access:https://doi.org/10.1002/cam4.2547

Internet

https://doi.org/10.1002/cam4.2547

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