ABLE: blockwise site frequency spectra for inferring complex population histories and recombination

ABLE: blockwise site frequency spectra for inferring complex population histories and recombination

Abstract We introduce ABLE (Approximate Blockwise Likelihood Estimation), a novel simulation-based composite likelihood method that uses the blockwise site frequency spectrum to jointly infer past demography and recombination. ABLE is explicitly designed for a wide variety of data from unphased dipl...

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Bibliographic Details
Main Authors: Champak R. Beeravolu, Michael J. Hickerson, Laurent A. F. Frantz, Konrad Lohse
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Genome Biology
Subjects:
Inference
Population history
Composite likelihood
Recombination
Admixture
Orangutan
Online Access:http://link.springer.com/article/10.1186/s13059-018-1517-y

Internet

http://link.springer.com/article/10.1186/s13059-018-1517-y

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