Complement protein levels in plasma astrocyte‐derived exosomes are abnormal in conversion from mild cognitive impairment to Alzheimer's disease dementia

Complement protein levels in plasma astrocyte‐derived exosomes are abnormal in conversion from mild cognitive impairment to Alzheimer's disease dementia

Abstract Introduction Levels of complement proteins (CPs) in plasma astrocyte‐derived exosomes (ADEs) that are abnormal in Alzheimer's disease (AD) have not been assessed in mild cognitive impairment (MCI). Methods Participants (n = 20 per group) had either MCI converting to dementia within 3 y...

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Bibliographic Details
Main Authors: Charisse N. Winston, Edward J. Goetzl, Janice B. Schwartz, Fanny M. Elahi, Robert A. Rissman
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
Neuroinflammation
Neurodegeneration
Biomarkers
Cognitive loss
Complement regulators
Online Access:https://doi.org/10.1016/j.dadm.2018.11.002

Internet

https://doi.org/10.1016/j.dadm.2018.11.002

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