Pho dynamically interacts with Spt5 to facilitate transcriptional switches at the hsp70 locus

Pho dynamically interacts with Spt5 to facilitate transcriptional switches at the hsp70 locus

Abstract Background Numerous target genes of the Polycomb group (PcG) are transiently activated by a stimulus and subsequently repressed. However, mechanisms by which PcG proteins regulate such target genes remain elusive. Results We employed the heat shock-responsive hsp70 locus in Drosophila to st...

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Bibliographic Details
Main Authors: Allwyn Pereira, Renato Paro
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Epigenetics & Chromatin
Subjects:
Heat shock
Pol II pausing
Polycomb proteins
Protein–protein interactions
Transcriptional activators
Online Access:http://link.springer.com/article/10.1186/s13072-017-0166-9

Internet

http://link.springer.com/article/10.1186/s13072-017-0166-9

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