Quantitative proteomic profiling of white matter in cases of cerebral amyloid angiopathy reveals upregulation of extracellular matrix proteins and clusterin
Aims: Cerebral amyloid angiopathy (CAA) is the accumulation of amyloid beta (Aβ) in the walls of cerebral arterioles, arteries and capillaries. Changes in the white matter in CAA are observed as hyperintensities and dilated perivascular spaces on MRI suggesting impairment of fluid drainage but the p...
Main Authors: | Antigoni Manousopoulou, Ho Ming Yuen, Matt MacGregor Sharp, Satoshi Saito, Roxana Aldea, Norman Mazer, Spiros D Garbis, Roxana O Carare |
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Format: | Article |
Language: | English |
Published: |
University of Münster / Open Journals System
2020-10-01
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Series: | Free Neuropathology |
Subjects: | |
Online Access: | https://www.uni-muenster.de/Ejournals/index.php/fnp/article/view/2955 |
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