Dysregulation of Cell Survival in Diffuse Large B Cell Lymphoma: Mechanisms and Therapeutic Targets

Dysregulation of Cell Survival in Diffuse Large B Cell Lymphoma: Mechanisms and Therapeutic Targets

Diffuse large B cell lymphoma (DLBCL) is the most common type of lymphoma worldwide, representing 30–40% of non-Hodgkin lymphomas, and is clinically aggressive. Although more than half of patients with DLBCL are cured by using standard first-line immunochemotherapy, the remaining patients are refrac...

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Bibliographic Details
Main Authors: Yi Miao, L. Jeffrey Medeiros, Zijun Y. Xu-Monette, Jianyong Li, Ken H. Young
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Oncology
Subjects:
DLBCL
cell survival
apoptosis
BCR signaling
BCL2
p53
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00107/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00107/full

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