DNA methylation in the malignant transformation of meningiomas.

Meningiomas are central nervous system tumors that originate from the meningeal coverings of the brain and spinal cord. Most meningiomas are pathologically benign or atypical, but 3-5% display malignant features. Despite previous studies on benign and atypical meningiomas, the key molecular pathways...

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Bibliographic Details
Main Authors: Fan Gao, Lingling Shi, Jonathan Russin, Liyun Zeng, Xiao Chang, Shuhan He, Thomas C Chen, Steven L Giannotta, Daniel J Weisenberger, Gabriel Zada, William J Mack, Kai Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3551961?pdf=render