Functional Analysis of Hydrolethalus Syndrome Protein HYLS1 in Ciliogenesis and Spermatogenesis in Drosophila

Functional Analysis of Hydrolethalus Syndrome Protein HYLS1 in Ciliogenesis and Spermatogenesis in Drosophila

Cilia and flagella are conserved subcellular organelles, which arise from centrioles and play critical roles in development and reproduction of eukaryotes. Dysfunction of cilia leads to life-threatening ciliopathies. HYLS1 is an evolutionarily conserved centriole protein, which is critical for cilio...

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Bibliographic Details
Main Authors: Yanan Hou, Zhimao Wu, Yingying Zhang, Huicheng Chen, Jinghua Hu, Yi Guo, Ying Peng, Qing Wei
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
HYLS1
ciliogenesis
ciliary gate
PCL
centriole elongation
spermatogenesis
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00301/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.00301/full

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