Modeling the Dynamics of Acute Phase Protein Expression in Human Hepatoma Cells Stimulated by IL-6

Interleukin-6 (IL-6) is a systemic inflammatory mediator that triggers the human body’s acute phase response to trauma or inflammation. Although mathematical models for IL-6 signaling pathways have previously been developed, reactions that describe the expression of acute phase proteins were not inc...

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Bibliographic Details
Main Authors: Zhaobin Xu, Jens O. M. Karlsson, Zuyi Huang
Format: Article
Language:English
Published: MDPI AG 2015-01-01
Series:Processes
Subjects:
Online Access:http://www.mdpi.com/2227-9717/3/1/50