Indole Signaling at the Host-Microbiota-Pathogen Interface

Pathogens sense and respond to several small molecules within the GI tract to modulate expression of their virulence repertoire. Indole is a signaling molecule produced by the gut microbiota. Here we show that indole concentrations are higher in the lumen, where the microbiota is present, than in th...

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Bibliographic Details
Main Authors: Aman Kumar, Vanessa Sperandio
Format: Article
Language:English
Published: American Society for Microbiology 2019-06-01
Series:mBio
Subjects:
Online Access:https://doi.org/10.1128/mBio.01031-19