Capsids and Genomes of Jumbo-Sized Bacteriophages Reveal the Evolutionary Reach of the HK97 Fold

Large icosahedral viruses that infect bacteria represent an extreme of the coevolution of capsids and the genomes they accommodate. One subset of these large viruses is the jumbophages, tailed phages with double-stranded DNA genomes of at least 200,000 bp. We explored the mechanism leading to increa...

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Bibliographic Details
Main Authors: Jianfei Hua, Alexis Huet, Carlos A. Lopez, Katerina Toropova, Welkin H. Pope, Robert L. Duda, Roger W. Hendrix, James F. Conway, Vincent R. Racaniello
Format: Article
Language:English
Published: American Society for Microbiology 2017-10-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/5/e01579-17