Unilateral Botulinum Neurotoxin-A Injection into the Striatum of C57BL/6 Mice Leads to a Different Motor Behavior Compared with Rats

Unilateral Botulinum Neurotoxin-A Injection into the Striatum of C57BL/6 Mice Leads to a Different Motor Behavior Compared with Rats

Different morphological changes in the caudate-putamen (CPu) of naïve rats and mice were observed after intrastriatal botulinum neurotoxin-A (BoNT-A) injection. For this purpose we here studied various motor behaviors in mice (n = 46) longitudinally up to 9 months after intrastriatal BoNT-A...

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Bibliographic Details
Main Authors: Veronica Antipova, Andreas Wree, Carsten Holzmann, Teresa Mann, Nicola Palomero-Gallagher, Karl Zilles, Oliver Schmitt, Alexander Hawlitschka
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Toxins
Subjects:
botulinum neurotoxin-A
basal ganglia
interspecies differences in motor behavior
mouse
rat
interneurons
Online Access:http://www.mdpi.com/2072-6651/10/7/295

Internet

http://www.mdpi.com/2072-6651/10/7/295

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