Anti-alcohol and anxiolytic properties of a new chemical entity, GET73

Anti-alcohol and anxiolytic properties of a new chemical entity, GET73

N-[(4-trifluoromethyl)benzyl]4-methoxybutyramide (GET73) is a newly synthesized compound structurally related to the clinically used, alcohol-substituting agent, gamma-hydroxybutyric acid (GHB). The present study was designed to assess whether GET73 may share with GHB the capacity to reduce alcohol...

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Bibliographic Details
Main Authors: Antonella eLoche, Francesco eSimonetti, Carla eLobina, Mauro A M Carai, Giancarlo eColombo, Paola eCastelli, Domenico eBarone, Roberto eCacciaglia
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-02-01
Series:Frontiers in Psychiatry
Subjects:
alcohol deprivation effect
alcohol intake
anxiety-related behaviors
GET73
Sardinian alcohol-preferring (sP) rats
γ-hydroxybutyric acid (GHB)
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpsyt.2012.00008/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fpsyt.2012.00008/full

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