Phase I and II Clinical Trial Comparing the LBSap, Leishmune<sup>®</sup>, and Leish-Tec<sup>®</sup> Vaccines against Canine Visceral Leishmaniasis

Phase I and II Clinical Trial Comparing the LBSap, Leishmune<sup>®</sup>, and Leish-Tec<sup>®</sup> Vaccines against Canine Visceral Leishmaniasis

In this study, we performed a phase I and II clinical trial in dogs to evaluate the toxicity and immunogenicity of LBSap-vaccine prototype, in comparison to Leishmune<sup>®</sup> and Leish-Tec<sup>®</sup> vaccines. Twenty-eight dogs were classified in four groups: (i) control...

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Bibliographic Details
Main Authors: Rodrigo Dian de Oliveira Aguiar-Soares, Bruno Mendes Roatt, Fernando Augusto Siqueira Mathias, Levi Eduardo Soares Reis, Jamille Mirelle de Oliveira Cardoso, Rory Cristiane Fortes de Brito, Henrique Gama Ker, Rodrigo Corrêa-Oliveira, Rodolfo Cordeiro Giunchetti, Alexandre Barbosa Reis
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Vaccines
Subjects:
visceral leishmaniasis
vaccines
LBSap
Leishmune<sup>®</sup>, Leish-Tec<sup>®</sup>, <i>Leishmania infantum</i>
dog
Online Access:https://www.mdpi.com/2076-393X/8/4/690

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https://www.mdpi.com/2076-393X/8/4/690

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