Cardioprotective Effectiveness of a Combination of 2-Ethyl-6-Methyl-3-Hydroxypyridine Enantiomers and Rosuvastatin in a Model of Doxorubicin Cardiomyopathy

Cardioprotective Effectiveness of a Combination of 2-Ethyl-6-Methyl-3-Hydroxypyridine Enantiomers and Rosuvastatin in a Model of Doxorubicin Cardiomyopathy

Aim. To study the cardioprotective effect of levorotatory ethylmethylhydroxypyridine malate enantiomer in combination with rosuvastatin on the model of doxorubicin cardiomyopathy.Material and methods. The research was conducted using 80 Langendorff perfused Wistar rat hearts (OOO “Kardioprotekt”, Sa...

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Bibliographic Details
Main Authors: Pavel D. Kolesnichenko, Ekaterina G. Pokhvoshcheva, Ekaterina S. Chakina, Konstantin M. Reznikov, Irina A. Popova, Irina N. Dolzhikova
Format: Article
Language:Russian
Published: Ministry of Healthcare of the Russian Federation. “Kuban State Medical University” 2019-12-01
Series:Кубанский научный медицинский вестник
Subjects:
racemic mixture of ethylmethylhydroxypyridine malate enantiomers
levorotatory ethylmethylhydroxypyridine malate enantiomer
doxorubicin cardiomyopathy
langendorf isolated heart
“diastolic defect”
Online Access:https://ksma.elpub.ru/jour/article/view/2018

Internet

https://ksma.elpub.ru/jour/article/view/2018

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