TrkA regulates the regenerative capacity of bone marrow stromal stem cells in nerve grafts

TrkA regulates the regenerative capacity of bone marrow stromal stem cells in nerve grafts

We previously demonstrated that overexpression of tropomyosin receptor kinase A (TrkA) promotes the survival and Schwann cell-like differentiation of bone marrow stromal stem cells in nerve grafts, thereby enhancing the regeneration and functional recovery of the peripheral nerve. In the present stu...

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Bibliographic Details
Main Authors: Mei-Ge Zheng, Wen-Yuan Sui, Zhen-Dan He, Yan Liu, Yu-Lin Huang, Shu-Hua Mu, Xin-Zhong Xu, Ji-Sen Zhang, Jun-Le Qu, Jian Zhang, Dong Wang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; bone marrow stromal stem cells; tropomyosin receptor kinase A receptor; lentiviral vector; shRNA; extracellular signal-regulated protein kinases 1/2; Bcl-2; nerve grafts; peripheral nerve regeneration; survival; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=10;spage=1765;epage=1771;aulast=Zheng

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=10;spage=1765;epage=1771;aulast=Zheng

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