Development of a Premature Stop Codon-detection method based on a bacterial two-hybrid system

<p>Abstract</p> <p>Background</p> <p>The detection of Premature Stop Codons (PSCs) in human genes is very useful for the genetic diagnosis of different hereditary cancers, e.g. Familial Breast Cancer and Hereditary Non-Polyposis Colorectal Cancer (HNPCC). The products o...

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Bibliographic Details
Main Authors: Mayorga Luis S, Gomez Laura C, Marzese Diego M, Real Sebastián M, Roqué María
Format: Article
Language:English
Published: BMC 2006-09-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/6/38