Exploring the Variable Phenotypes of <i>RPGR</i> Carrier Females in Assessing Their Potential for Retinal Gene Therapy

Exploring the Variable Phenotypes of <i>RPGR</i> Carrier Females in Assessing Their Potential for Retinal Gene Therapy

Inherited retinal degenerations are the leading cause of blindness in the working population. X-linked retinitis pigmentosa (XLRP), caused by mutations in the Retinitis pigmentosa GTPase regulator (<i>RPGR</i>) gene is one of the more severe forms, and female carriers of <i>RPGR<...

Full description

Bibliographic Details
Main Authors: Anika Nanda, Anna P. Salvetti, Penny Clouston, Susan M. Downes, Robert E. MacLaren
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Genes
Subjects:
inherited retinal degeneration
retinitis pigmentosa
pigmentary retinopathy
X-linked retinitis pigmentosa
retinitis pigmentosa GTPase regulator gene (<i>RPGR</i>)
female carriers
X-inactivation
skewed X-inactivation
gene therapy
Online Access:https://www.mdpi.com/2073-4425/9/12/643

Internet

https://www.mdpi.com/2073-4425/9/12/643

Similar Items