Yerba mate tea (Ilex paraguariensis): Phenolics, antioxidant capacity and in vitro inhibition of colon cancer cell proliferation
Mate tea (MT) is a rich source of phenolic compounds that vary depending on geographical origin and mode of preparation. Total phenolic concentration and antioxidant capacity of Mate tea (Ilex paraguariensis) products were determined in this work. In addition, a representative MT was tested for in v...
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doaj-f475ac54d18a401f98199446c77afce32021-04-29T04:39:47ZengElsevierJournal of Functional Foods1756-46462010-01-01212334Yerba mate tea (Ilex paraguariensis): Phenolics, antioxidant capacity and in vitro inhibition of colon cancer cell proliferationElvira González de Mejía0Young Soo Song1Caleb I. Heck2MarcoVinicio Ramírez-Mares3Department of Food Science and Human Nutrition, University of Illinois at Urbana-Champaign, 228 ERML, MC-051, 1201 W. Gregory Drive, Urbana, IL 61801, USA; Corresponding author: Address: 228 ERML, 1201 W. Gregory Drive, Urbana, Illinois 61801, USA. Tel.: +1 (217) 244 3196; fax: +1 (217) 265 0925.Department of Food Science and Human Nutrition, University of Illinois at Urbana-Champaign, 228 ERML, MC-051, 1201 W. Gregory Drive, Urbana, IL 61801, USADepartment of Food Science and Human Nutrition, University of Illinois at Urbana-Champaign, 228 ERML, MC-051, 1201 W. Gregory Drive, Urbana, IL 61801, USAResources Institute, University Del Mar, Oaxaca 70902, MexicoMate tea (MT) is a rich source of phenolic compounds that vary depending on geographical origin and mode of preparation. Total phenolic concentration and antioxidant capacity of Mate tea (Ilex paraguariensis) products were determined in this work. In addition, a representative MT was tested for in vitro inhibition of human colon carcinoma cell proliferation. Total polyphenol concentration, was measured using Folin–Ciocalteau method, ranged from 90 to 176 mg gallic acid eq (GAE)/g dry leaves (DL) in traditional MT and from 40 to 113 mg GAE/g DL in MT added with other flavouring ingredients. It was estimated that a cup of tea (250 ml) containing one teaspoon (5 g) of instant MT could provide an average intake of 1.5 g GAE. Fresh tea (FT) from Mate leaves displayed high antioxidant capacity (85 ± 1%) and preferentially inhibited 50% of net growth of human colorectal adenocarcinoma cells CaCo-2 (GI50 = 1.0 ± 0.03 μg/ml) and HT-29 (GI50 = 105.2 ± 15.2 μg/ml) when compared with the CCD-33Co normal colon fibroblast cell line (GI50 > 300 μg/ml). MT inhibited in vitro colon cancer cell proliferation possibly mediated via pro-oxidant activities, therefore represents a potential source of chemopreventive agents that deserve further investigation.http://www.sciencedirect.com/science/article/pii/S1756464609000814Mate teaIlex paraguariensisPhenolicsAntioxidant capacityDPPHColon cancer |
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DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Elvira González de Mejía Young Soo Song Caleb I. Heck MarcoVinicio Ramírez-Mares |
spellingShingle |
Elvira González de Mejía Young Soo Song Caleb I. Heck MarcoVinicio Ramírez-Mares Yerba mate tea (Ilex paraguariensis): Phenolics, antioxidant capacity and in vitro inhibition of colon cancer cell proliferation Journal of Functional Foods Mate tea Ilex paraguariensis Phenolics Antioxidant capacity DPPH Colon cancer |
author_facet |
Elvira González de Mejía Young Soo Song Caleb I. Heck MarcoVinicio Ramírez-Mares |
author_sort |
Elvira González de Mejía |
title |
Yerba mate tea (Ilex paraguariensis): Phenolics, antioxidant capacity and in vitro inhibition of colon cancer cell proliferation |
title_short |
Yerba mate tea (Ilex paraguariensis): Phenolics, antioxidant capacity and in vitro inhibition of colon cancer cell proliferation |
title_full |
Yerba mate tea (Ilex paraguariensis): Phenolics, antioxidant capacity and in vitro inhibition of colon cancer cell proliferation |
title_fullStr |
Yerba mate tea (Ilex paraguariensis): Phenolics, antioxidant capacity and in vitro inhibition of colon cancer cell proliferation |
title_full_unstemmed |
Yerba mate tea (Ilex paraguariensis): Phenolics, antioxidant capacity and in vitro inhibition of colon cancer cell proliferation |
title_sort |
yerba mate tea (ilex paraguariensis): phenolics, antioxidant capacity and in vitro inhibition of colon cancer cell proliferation |
publisher |
Elsevier |
series |
Journal of Functional Foods |
issn |
1756-4646 |
publishDate |
2010-01-01 |
description |
Mate tea (MT) is a rich source of phenolic compounds that vary depending on geographical origin and mode of preparation. Total phenolic concentration and antioxidant capacity of Mate tea (Ilex paraguariensis) products were determined in this work. In addition, a representative MT was tested for in vitro inhibition of human colon carcinoma cell proliferation. Total polyphenol concentration, was measured using Folin–Ciocalteau method, ranged from 90 to 176 mg gallic acid eq (GAE)/g dry leaves (DL) in traditional MT and from 40 to 113 mg GAE/g DL in MT added with other flavouring ingredients. It was estimated that a cup of tea (250 ml) containing one teaspoon (5 g) of instant MT could provide an average intake of 1.5 g GAE. Fresh tea (FT) from Mate leaves displayed high antioxidant capacity (85 ± 1%) and preferentially inhibited 50% of net growth of human colorectal adenocarcinoma cells CaCo-2 (GI50 = 1.0 ± 0.03 μg/ml) and HT-29 (GI50 = 105.2 ± 15.2 μg/ml) when compared with the CCD-33Co normal colon fibroblast cell line (GI50 > 300 μg/ml). MT inhibited in vitro colon cancer cell proliferation possibly mediated via pro-oxidant activities, therefore represents a potential source of chemopreventive agents that deserve further investigation. |
topic |
Mate tea Ilex paraguariensis Phenolics Antioxidant capacity DPPH Colon cancer |
url |
http://www.sciencedirect.com/science/article/pii/S1756464609000814 |
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