Diallyl sulfide attenuates transforming growth factor-β-stimulated pulmonary fibrosis through Nrf2 activation in lung MRC-5 fibroblast

Idiopathic pulmonary fibrosis accounts for the lethal diffuse fibrosing lung disease, which is described with accumulation of fibroblasts, the loss and damage of lung epithelial cells, and causing respiratory failure. Excessive ROS level impairs the cellular redox level, inflammatory cell infiltrati...

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Bibliographic Details
Main Authors: Cheng-Ying Ho, Chi-Cheng Lu, Jhih-Jia Jhang, Gow-Chin Yen
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464616303437