A randomized open-label trial to evaluate the efficacy and safety of triple therapy with aspirin, atorvastatin, and nicorandil in hospitalised patients with SARS Cov-2 infection: A structured summary of a study protocol for a randomized controlled trial

A randomized open-label trial to evaluate the efficacy and safety of triple therapy with aspirin, atorvastatin, and nicorandil in hospitalised patients with SARS Cov-2 infection: A structured summary of a study protocol for a randomized controlled trial

Abstract Objectives The pathophysiology of SARS-Cov-2 is characterized by inflammation, immune dysregulation, coagulopathy, and endothelial dysfunction. No single therapeutic agent can target all these pathophysiologic substrates. Moreover, the current therapies are not fully effective in reducing m...

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Bibliographic Details
Main Authors: Ambudhar Sharma, Charu Sharma, Sujeet Raina, Balraj Singh, Devendra Singh Dadhwal, Vinay Dogra, Swatantra Gupta, Shyam Bhandari, Vivek Sood
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Trials
Subjects:
COVID-19
Aspirin
Atorvastatin
Nicorandil
Randomised control trial
Protocol
Online Access:https://doi.org/10.1186/s13063-021-05361-y

Internet

https://doi.org/10.1186/s13063-021-05361-y

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