Frequency of genetic polymorphisms of PXR gene in the Brazilian population
INTRODUCTION: PXR polymorphisms have been implicated in modulating CYP3A4 and PXR expression, potentially accounting for interindividual differences in drug metabolism. The prevalence of PXR polymorphisms varies among ethnic groups and data on the allelic distribution in the highly mixed Brazilian p...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Faculdade de Medicina / USP
2011-01-01
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| Series: | Clinics |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322011000600020 |