Renal Reabsorption of Folates: Pharmacological and Toxicological Snapshots

Folates are water-soluble B9 vitamins that serve as one-carbon donors in the de novo synthesis of thymidylate and purines, and in the conversion of homocysteine to methionine. Due to their key roles in nucleic acid synthesis and in DNA methylation, inhibiting the folate pathway is still one of the m...

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Bibliographic Details
Main Authors: Sophia L Samodelov, Zhibo Gai, Gerd A Kullak-Ublick, Michele Visentin
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/11/10/2353