Optimization of Vapor Diffusion Conditions for Anti-CD20 Crystallization and Scale-Up to Meso Batch

The crystal form is one of the preferred formulations for biotherapeutics, especially thanks to its ability to ensure high stability of the active ingredient. In addition, crystallization allows the recovery of a very pure drug, thus facilitating the manufacturing process. However, in many cases, cr...

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Bibliographic Details
Main Authors: Huaiyu Yang, Benny Danilo Belviso, Xiaoyu Li, Wenqian Chen, Teresa Fina Mastropietro, Gianluca Di Profio, Rocco Caliandro, Jerry Y. Y. Heng
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Crystals
Subjects:
Online Access:https://www.mdpi.com/2073-4352/9/5/230