CD25 appears non essential for human peripheral T(reg) maintenance in vivo.

IL-2 has been reported to be critical for peripheral T(reg) survival in mouse models. Here, we examined T(reg) maintenance in a series of paediatric liver transplant recipients who received basiliximab, a therapeutic anti-CD25 monoclonal antibody.FoxP3+ CD4 T cells were analyzed by flow cytometry be...

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Bibliographic Details
Main Authors: Marie-Ghislaine de Goër de Herve, Emmanuel Gonzales, Houria Hendel-Chavez, Jean-Luc Décline, Olivia Mourier, Karim Abbed, Emmanuel Jacquemin, Yassine Taoufik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2912775?pdf=render