Inhibitory Influence of Panax notoginseng Saponins on Aspirin Hydrolysis in Human Intestinal Caco-2 Cells

Inhibitory Influence of Panax notoginseng Saponins on Aspirin Hydrolysis in Human Intestinal Caco-2 Cells

Herb-drug interactions are important safety concerns in clinical practice. The interactions occur firstly in the intestinal absorption for orally administered drugs. Aspirin and Panax notoginseng saponins (PNS)-based drugs are often combined in China to prevent larger-artery atherosclerosis. Here, w...

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Bibliographic Details
Main Authors: Zongxi Sun, Yali Wu, Bing Yang, Baochen Zhu, Shaonan Hu, Yang Lu, Bo Zhao, Shouying Du
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Molecules
Subjects:
Panax notoginseng saponins
aspirin
Caco-2 cells
intestinal absorption
carboxylesterase
Online Access:http://www.mdpi.com/1420-3049/23/2/455

Internet

http://www.mdpi.com/1420-3049/23/2/455

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