Autophagy and mTOR signaling during intervertebral disc aging and degeneration

Abstract Degenerative disc disease is a highly prevalent, global health problem that represents the primary cause of back pain and is associated with neurological disorders, including radiculopathy, myelopathy, and paralysis, resulting in worker disability and socioeconomic burdens. The intervertebr...

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Bibliographic Details
Main Authors: Takashi Yurube, Masaaki Ito, Yuji Kakiuchi, Ryosuke Kuroda, Kenichiro Kakutani
Format: Article
Language:English
Published: Wiley 2020-03-01
Series:JOR Spine
Subjects:
Online Access:https://doi.org/10.1002/jsp2.1082