MicroRNAs in Gene Regulation: When the Smallest Governs It All

Encoded by the genome of most eukaryotes examined so far, microRNAs (miRNAs) are small ~21-nucleotide (nt) noncoding RNAs (ncRNAs) derived from a biosynthetic cascade involving sequential processing steps executed by the ribonucleases (RNases) III Drosha and Dicer. Following their recent identificat...

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Bibliographic Details
Main Authors: Dominique L. Ouellet, Marjorie P. Perron, Lise-Andrée Gobeil, Pierre Plante, Patrick Provost
Format: Article
Language:English
Published: Hindawi Limited 2006-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/JBB/2006/69616