Airway CD8+CD161++TCRvα7.2+ T Cell Depletion During Untreated HIV Infection Targets CD103 Expressing Cells

Airway CD8+CD161++TCRvα7.2+ T Cell Depletion During Untreated HIV Infection Targets CD103 Expressing Cells

HIV-infected adults are at an increased risk to lower respiratory tract infections (LRTIs). CD8+CD161++TCRvα7.2+ T cells are an innate-like T cell subset that are thought to play an important role in early defense against pathogens in the respiratory tract. HIV infection leads to irreversible deplet...

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Bibliographic Details
Main Authors: Leonard Mvaya, Andrew Mwale, Annemarie Hummel, Joseph Phiri, Raphael Kamng'ona, David Mzinza, Elizabeth Chimbayo, Rose Malamba, Anstead Kankwatira, Henry C. Mwandumba, Kondwani C. Jambo
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
airway
HIV
CD103
CD8 T cell
adult
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02003/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02003/full

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