Species and strain glycosylation patterns of PrPSc.

Species and strain glycosylation patterns of PrPSc.

BACKGROUND: A key event in transmissible spongiform encephalopathies (TSEs) is the conversion of the soluble, protease-sensitive glycosylated prion protein (PrP(C)) to an abnormally structured, aggregated and partially protease-resistant isoform (PrP(Sc)). Both PrP isoforms bear two potential glycos...

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Bibliographic Details
Main Authors: Konstantinos Xanthopoulos, Magdalini Polymenidou, Sue J Bellworthy, Sylvie L Benestad, Theodoros Sklaviadis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2680983?pdf=render

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http://europepmc.org/articles/PMC2680983?pdf=render

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