A new mouse SNP genotyping assay for speed congenics: combining flexibility, affordability, and power

A new mouse SNP genotyping assay for speed congenics: combining flexibility, affordability, and power

Abstract Background Speed congenics is an important tool for creating congenic mice to investigate gene functions, but current SNP genotyping methods for speed congenics are expensive. These methods usually rely on chip or array technologies, and a different assay must be developed for each backcros...

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Bibliographic Details
Main Authors: Kimberly R. Andrews, Samuel S. Hunter, Brandi K. Torrevillas, Nora Céspedes, Sarah M. Garrison, Jessica Strickland, Delaney Wagers, Gretchen Hansten, Daniel D. New, Matthew W. Fagnan, Shirley Luckhart
Format: Article
Language:English
Published: BMC 2021-05-01
Series:BMC Genomics
Subjects:
Speed congenics
Illumina
Next generation sequencing
Allegro targeted genotyping
Single primer enrichment technology
Bioinformatic pipeline
Online Access:https://doi.org/10.1186/s12864-021-07698-9

Internet

https://doi.org/10.1186/s12864-021-07698-9

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