ROS generation and autophagosome accumulation contribute to the DMAMCL-induced inhibition of glioma cell proliferation by regulating the ROS/MAPK signaling pathway and suppressing the Akt/mTOR signaling pathway

Yanjun Wang,1 Jiachen Zhang,1 Yihang Yang,1 Qian Liu,2 Guangming Xu,1 Rui Zhang,1 Qi Pang1 1Department of Neurosurgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, 250021, Shandong, China; 2Department of Histology and Embryology, Shandong University Cheeloo College Medici...

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Bibliographic Details
Main Authors: Wang Y, Zhang J, Yang Y, Liu Q, Xu G, Zhang R, Pang Q
Format: Article
Language:English
Published: Dove Medical Press 2019-03-01
Series:OncoTargets and Therapy
Subjects:
ROS
Online Access:https://www.dovepress.com/ros-generation-and-autophagosome-accumulation-contribute-to-the-dmamcl-peer-reviewed-article-OTT