Phototriggerable 2',7-caged paclitaxel.

Three different variants of photoactivatable caged paclitaxel (PTX) have been synthesized and their bioactivity was characterized in in vitro assays and in living cells. The caged PTXs contain the photoremovable chromophore 4,5-dimethoxy-2-nitrobenzyloxycarbonyl (Nvoc) attached to position C7, C2�...

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Bibliographic Details
Main Authors: Radu A Gropeanu, Hella Baumann, Sandra Ritz, Volker Mailänder, Thomas Surrey, Aránzazu del Campo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3435387?pdf=render