Analysis of sphingolipids in human corneal fibroblasts from normal and keratoconus patients

The pathophysiology of human keratoconus (KC), a bilateral progressive corneal disease leading to protrusion of the cornea, stromal thinning, and scarring, is not well-understood. In this study, we investigated a novel sphingolipid (SPL) signaling pathway through which KC may be regulated. Using hum...

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Bibliographic Details
Main Authors: Hui Qi, Shrestha Priyadarsini, Sarah E. Nicholas, Akhee Sarker-Nag, Jeremy Allegood, Charles E. Chalfant, Nawajes A. Mandal, Dimitrios Karamichos
Format: Article
Language:English
Published: Elsevier 2017-04-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520338426