Icaritin, an exogenous phytomolecule, enhances osteogenesis but not angiogenesis--an in vitro efficacy study.

We found that Icaritin, an intestinal metabolite of Epimedium-derived flavonoids (EF) enhanced osteoblastic differentiation of mesenchymal stem cells (MSCs) only under osteogenic induction conditions. We also demonstrated its effect on inhibition of adipogenic differentiation of MSCs. Unlike the fin...

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Bibliographic Details
Main Authors: Dong Yao, Xin-Hui Xie, Xin-Luan Wang, Chao Wan, Yuk-Wai Lee, Shi-Hui Chen, Duan-Qing Pei, Yi-Xiang Wang, Gang Li, Ling Qin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3431393?pdf=render