Evaluating the Effect of Serine Proteases on Collagenase Activity during Human Islet Isolation
Inconsistencies in human islet yields after collagenase digestion have been attributed to the activation of endogenous enzymes of the donor pancreas. It has been suggested that pancreatic serine proteases contribute to the proteolysis of collagenase. This study defined the effects of endogenous enzy...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2002-11-01
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Series: | Cell Transplantation |
Online Access: | https://doi.org/10.3727/000000002783985279 |