Evaluating the Effect of Serine Proteases on Collagenase Activity during Human Islet Isolation

Inconsistencies in human islet yields after collagenase digestion have been attributed to the activation of endogenous enzymes of the donor pancreas. It has been suggested that pancreatic serine proteases contribute to the proteolysis of collagenase. This study defined the effects of endogenous enzy...

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Bibliographic Details
Main Authors: Natisha L. Rose, Monica M. Palcic, Jonathan R. T. Lakey Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2002-11-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000002783985279