Targeting of the Cancer-Associated Fibroblast—T-Cell Axis in Solid Malignancies

The introduction of a wide range of immunotherapies in clinical practice has revolutionized the treatment of cancer in the last decade. The majority of these therapeutic modalities are centered on reinvigorating a tumor-reactive cytotoxic T-cell response. While impressive clinical successes are obta...

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Bibliographic Details
Main Authors: Tom J. Harryvan, Els M. E. Verdegaal, James C. H. Hardwick, Lukas J. A. C. Hawinkels, Sjoerd H. van der Burg
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/8/11/1989