Functional characterization improves associations between rare non-synonymous variants in CHRNB4 and smoking behavior.

Functional characterization improves associations between rare non-synonymous variants in CHRNB4 and smoking behavior.

Smoking is the leading cause of preventable death worldwide. Accordingly, effort has been devoted to determining the genetic variants that contribute to smoking risk. Genome-wide association studies have identified several variants in nicotinic acetylcholine receptor genes that contribute to nicotin...

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Bibliographic Details
Main Authors: Gabe Haller, Ping Li, Caroline Esch, Simon Hsu, Alison M Goate, Joe Henry Steinbach
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4013067?pdf=render

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http://europepmc.org/articles/PMC4013067?pdf=render

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